title: THE KINGDOM OF GOD AND THE ASSEMBLY OF THE PEOPLE: THE ROLE OF THE SYNAGOGUE IN THE AIMS OF JESUS

title: The Role of the Synagogue in the Aims of Jesus

contributor:
Runesson, Anders
Religious Studies

subject: Jesus, Gospels, history, historiography, historical Jesus, synagogue, early synagogues, early Christianity, Gospel of Luke, religious studies, biblical studies, early Judaism

abstract:
The four canonical Gospels describe the synagogues of the Land of Israel as the primary locus of the public activities of Jesus of Nazareth. Despite the prominence of synagogues in the extant accounts of Jesus’ life and career, academic research on early synagogues has not yet played a significant role in the study of the historical Jesus. This project incorporates the findings of recent research on ancient synagogues into the study of the historical Jesus. So doing helps to recover a piece of Jesus’ early Jewish context that has been frequently neglected or misunderstood in previous scholarship.
This thesis has two related goals. The first is to contextualize Jesus’ activities in synagogues in light of current research on ancient synagogues. The second is to determine the role that the institution of the synagogue played in the aims of Jesus. I argue that the evidence indicates that the synagogue was intrinsic rather than incidental to Jesus’ mission, and that it was both the vehicle and the means by which he intended to realize his aim of the restoration of Israel. The historical investigation in this project helps to clarify our understanding of Jesus’ mission and also helps us to better understand the data involving synagogues in the Gospels. My examination of the evidence finds that the narratives involving synagogues in the Gospels accurately reflect an ancient synagogue setting, and can be better understood in light of current scholarship on synagogues. This speaks in favour of the historical plausibility of these narratives, and highlights the importance of the institutional setting of the synagogue for the interpretation of this data.

abstract: Dissertation

abstract: Doctor of Philosophy (PhD)

abstract: The four canonical Gospels describe the synagogues of the Land of Israel as the primary locus of the public activities of Jesus of Nazareth. Despite the prominence of synagogues in the accounts of Jesus’ life and career, academic research on early synagogues has not yet played a significant role in the study of the historical Jesus. This project has two related goals. The first is to contextualize Jesus’ activities in synagogues in light of current research on ancient synagogues. The second is to determine the role that the institution of the synagogue played in the aims of Jesus. I argue that the evidence indicates that the synagogue was intrinsic rather than incidental to Jesus’ mission, and that it was both the vehicle and the means by which he intended to realize his aim of the restoration of Israel.


title: Studies on Incorporation of 14C into Carrageenan and Methods of Localizing Carrageenan in Animal Tissues

contributor:
McCandless, E. L.
Biology

subject: Carrageenan, incorporation, localizing, animal, tissues, Lambda, polysaccharides, photoassimilation

abstract:
 Lambda carrageenan when injected subcutaneously causes the formation of a connective tissue granuloma. Initially there is a proliferation of connective tissue elements up to about fourteen days followed by regression so that by six weeks most collagenous tissue has
disappeared and been replaced by adipose tissue. Lambda carrageenan has been identified in the granuloma by staining reactions with toluidine blue and other stains for acid polysaccharides. The present study was undertaken to localize the carrageenan by means of fluorescent antibody and autoradiography. For this purpose labelling of carrageenan by photoassimilation of 14CO2 into carrageenan was done. Different parameters affecting the incorporation of 14C into the carrageenan fractions were studied.

abstract: Thesis

abstract: Master of Science (MSc)


title: Pollen-Climate Transfer Functions for the Western Interior of Canada

contributor:
MacDonald, Glen
Geography

subject: pollen-climate, transfer, functions, western interior

abstract:
 The objective of this project was to construct pollen-climate transfer functions for the Western Interior of Canada and to apply these to dated fossil pollen records to obtain estimates of past climates.

 Climate curves from the calibration functions were
constructed for summer precipitation and temperature, fall precipitation and temperature, winter temperature, and spring temperature.

 The palaeotemperature estimates suggest winter and fall temperatures were warmer during the mid-Holocene whereas the summer and spring temperatures suggest there was no significant difference in temperature between this time and the present. Results are not in accordance with the Milankovitch estimates of Holocene insolation variation or the conclusions of previous palaeoclimatic studies in the region.

 The palaeoprecipitation estimates constructed indicate decreased precipitation during the mid-Holocene. Increased aridity in the mid-Holocene is consistent with both the Milankovitch theory and the results of previous palaeoclimatic reconstructions from the study area. However, it is not clear if the high aridity reflects decreased precipitation or increased evapotranspiration.

 The theoretical and practical limitations of the
pollen-climate transfer function approach to this approach to the estimation of paleoclimates are discussed.

abstract: Thesis

abstract: Candidate in Philosophy


title: Three-Dimensional Relationships Among Traffic Flow Theory Variables: A Comparative Study

contributor:
Hall, Fred
Geography

subject: three-dimensional, relationships, traffic flow, variables, comparative, speed, volume, occupancy

abstract:
 This paper is a further investigation of Gilchrist and Hall's work on the three-dimensional relationships in traffic flow theory variables (Gilchrist and Hall, 1989). The investigation examines the three variables of traffic flow (speed, volume, and occupancy). Gilchrist and Hall's data is then compared with data used in this analysis. The traffic variables are first examined by the traditional two-dimensional model and then they are examined obliquely in
three-dimensional space. The resulting oblique views of the data are reviewed for points of agreement with conclusions made by Gilchrist and Hall. Resultant views of the data suggest that there is a plane along which all of the uncongested data fall. However, this phenomena only occurs when there is a wide range of speed values in the data set. The results also suggest that low-speed congested data do not lie on the same plane as do the uncongested data. It is concluded that low-speed congested data do not lie on a plane at all.

abstract: Thesis

abstract: Candidate in Philosophy


title: A Sense of Community in Co-operative Housing

contributor:
Eyles, John
Geography

subject: community, co-operative, housing

abstract:
 The purpose of this research paper is to examine the factors that are involved in providing a sense of community to the members of co-operative housing. Also, this investigation attempts to determine which factors influence the successful development of a sense of community within cooperative homes. The research hypothesis for this paper is to show that co-operative housing projects do provide its residents with a sense of community. The study was conducted by using data collected from two co-operative housing units in Hamilton: Apple Garth and Corktown Co-operative Homes. Information on residents' attitudes was collected by using a questionnaire through personal interviews. In order to test the hypothesis two statistical methods were utilized: chi-square and frequency tables. The results showed that co-op as a place to live' and neighbour' factors are most significant when investigating the attitudes' of residents in terms of a sense of community. Therefore, the conclusion is that the residents of Apple Garth and Corktown Co-operative Homes do experience a sense of community. The results have practical significance because researchers are encouraged to conduct studies of small groups (ie. the household) within cooperative
housing. This is critical since little is known about the motivations, expectations, likes and dislikes of the members of non-profit housing.

abstract: Thesis

abstract: Candidate in Philosophy


title: Pules Delays and Gain Characteristics in TEA CO2 Lasers

contributor:
Garside, B.K.
Ballik, E.A.
Physics

abstract: Title: Pulse Delays and Gain Characteristics in TEA CO2 Lasers, Author: John Reid, Location: Thode

abstract: A novel method is reported for studying the time-dependent gain and cavity losses in a TEA CO2 laser. The technique involves an investigation of the time delay of the onset of lasing with respect to the current pulse in such a laser. Detailed measurements of this time delay as both the laser gain and the cavity loss are varied, in conjunction with a simple theoretical analysis, permit the evaluation of parameters describing the time-dependent gain and the cavity loss. A refinement of the technique, using two amplifier tubes, allows an accurate measurement of the decay time of the gain.

abstract: Thesis

abstract: Master of Science (MS)


title: An Estimate of the Composition of Part of the Canadian Shield in Northwestern Ontario

contributor:
Shaw, D. M.
Geology

subject: composition, Canadian Shield, Precambrian rocks

abstract:
 An attempt has been made to estimate the abundance of trace and major constituents in the Precambrian surficial rocks in a large part (43,000 square miles) of the Red Lake - Lansdowne House area in northwestern Ontario. The area has an average composition which is
close to that of granodiorite, more silicic than most estimates of crustal abundance, close to other estimates for continental shield areas, but possibly deficient in K2O relative to Poldervaart's (1955) estimate. The rocks of this area appear to be low in Be, Ti, V, Cu, Y, Sc and Zr, and high in Sr, relative to crustal abundances based on the proportion of exposed rocks on the surface of the continents (Turekian and Wedepohl, 1961). Analysis of variance techniques have detected significant regional variations of Cr, Mn, Sr and Ba. Significant
variation exists between rock types for all trace elements analyzed except Cu.

abstract: Thesis

abstract: Master of Science (MSc)


title: Microwave Propagation in Rectangular Waveguide Containing Semiconductor Subject to Transverse Magnetic Field

contributor:
Gunn, M. W.
Electrical Engineering

subject:
Microwave Propagation
Rectangular Waveguide
Semiconductor Subject
transverse Magnetic Field

abstract:
 A detailed theoretical analysis of the propagation constant
and the field components in rectangular waveguide completely filled
with a semiconductor subjected to an external transverse applied
magnetic field, has been carried out. A numerical solution of the
transcendental equation for the propagation constant has been obtained
for the n-type germanium samples with different conductivities and
magnetic fields.

 An experimental verification of this theoretical analysis has
been made with a 22.2 ohm-em, n-type germanium sample at 9.46 GHz.
The applied transverse magnetic field was varied from 0 to 10 Kilogauss.
Measurements of the reflection co efficients at the air-semiconductor
interface for different values of the applied magnetic field have been
made with a high precision microwave reflection bridge. The
experimental results agree well with the theoretical results.

abstract: Thesis

abstract: Master of Engineering (MEngr)


title: Fast Neutron Cross Sections in the 2s-1d Shell

contributor:
Kennett, T. J.
Physics

subject: fast neutron, cross sections, shell, elements, resonances, nuclear

abstract:
 A new technique has be~n developed for the measurement of fast neutron total cross-sections in the range 0.8 -> 3.0 MeV using the fast neutrons from a reactor. The method was
used to obtain the cross-section of six elements in the 2s-1d shell. Various analytical techniques have been applied to measure the behavior of the average cross-sections and delineate the properties of the observed resonances. From these results the resonances are confirmed as examples of "doorway" states, and conclusions are drawn about the distributions
of the parameters of these states. The average properties are related to nuclear models of the origin and characteristics of states of high excitation in the target nuclides.

abstract: Thesis

abstract: Doctor of Philosophy (PhD)


abstract: Title: Development and Utilization of a Signal Averaging System, Author: T. B. Remple, Location: Thode

abstract:
A sampling oscilloscope was interfaced to a PDP11/10 minicomputer via one analog-to-digital converter (ADC) and one digital-to-analog converter (DAC), with the minicomputer being interfaced to a real time oscilloscope or plotter via two more DAC's. A software program that employed both assembler and Fortran was developed. This program controlled the signal averaging, did some data analysis, could output the data in normalized form onto a real time scope or a plotter, and also input and output the signal using punched type.

The usefulness of the system was then demonstrated by measuring the rise time of a short laser pulse through various lengths of graded index fibre, and the fibre response was extracted as a function of fibre length.

abstract: Thesis

abstract: Master of Engineering (ME)


title: Vacuum Ultraviolet Spectroscopy of the Cyanogen Halides

subject: vacuum, ultraviolet, spectroscopy, cyanogen halides, electronic

abstract:
 In Part I of this thesis, the design, construction, and calibration of a twenty-one foot off-plane Eagle vacuum spectrograph, a Lyman source, and predispersion unit are described.

 In Part II, the results of an investigation of the electronic absorption spectra of the cyanogen halides, obtained with the apparatus described in Part I, are given. Several electronic absorption systems have been observed for each of the cyanogen halides. These have been correlated and assigned to electronic transitions. Vibrational analyses have been made and the excited state dimensions have been determined by a quantitative application
of the Franck-Condon principle for two absorption systems of each of the cyanogen halides.

abstract: Thesis

abstract: Doctor of Philosophy (PhD)


contributor:
Sinha, N. K.
Electrical Engineering

abstract: Title: Application of a Vector Cost Function to Adaptive Control Systems Without Plant Identification, Author: Alain J-C. Rey, Location: Thode

abstract: The proposed Vector Cost Function technique for adaptive control of an unknown plant is investigated. The mathematical background of this algorithm is presented, and then the technique is applied to two second order plants, an over-damped one and an under-damped one, whose step responses are require. Also, the vector cost function parameters which affect the adapted responses of the plants are investigated, and finally the conclusions arrived at are presented.

abstract: Thesis

abstract: Master of Engineering (ME)


contributor:
Mueller, B.J.
Mathematics

abstract: Title: Extensions of the Krull-Schmidt-Azumaya Theorem, Author: Ronald W. Richards, Location: Thode

abstract:
The question which promoted this dissertation is the following: "How unique is a direct sum decomposition of a given R-module?" The classical result is tho direction is the so-called Krull-Schmitd-Azumaya Theorem, proved by Gorô Azumaya in [1]. It gives an answer to the question in the case that the given R-module is a direct sum of the sub-modules with local endomorphism ring. It is generalizations and extensions of this theorem that this paper is concerned with. The results of this thesis are stated and proved in a more general categorical setting than mod-R. Moreover, we do not resort to the embedding theorem, with the idea in mind that further generalization in those categories we are considering and similar results in other sort of categories may be suggested.

Chapter I lays some necessary categorical ground-work. In Chapter 2 we combine results of S. B. Conlon [2] and S. Elliger [4] within our categorical setting to obtain a generalization of the Krull-Schmidt-Azumaya Theorem. We consider representations of an object as an essential extension of a direct sum of summands (rather than simply direct sum decompositions), and we allow certain summands other than those with local endomorphism ring. Chapter 3, follow [10], (which was in turn applying the results of [3]) extends the concept of "local endomorphism ring" to the concept of "the exchange property" and produces certain coproduct uniqueness theorems. Finally, in Chapter 4, we consider decomposition of injectives and we see that certain problems involving coproduct decompositions can be eliminated in the case where the objects concerned are injective. We present a uniqueness theorem due to R.B. Warfield [10] and draw conclusions from this with the aid of the "spectral category" (which will be define and examined).

abstract: Thesis

abstract: Master of Science (MS)


title: Adaptive Nuclear Reactor Control Based on Optimal Low-order Linear Models

contributor:
Sinha, N.K.
Electrical Engineering

subject:
nuclear reactor
power level changes
low-order lineal models

abstract: The problem of adaptively controlling the power level changes of a nuclear reactor, by the use of a digital computer, is considered. It is established, that for the application of modern control theory a low-order linear model of the reactor is needed, but that the existing models are not sufficiently accurate-for the desired purpose. A new technique is therefore developed for finding low-order linear models of a given high-order system. Such models are shown to be suitable for the suboptimal control of the original system, subject to cost functions normally encountered in practice. The proposed methods of modelling and suboptimal control are applied to the adaptive control of a nuclear reactor. In order to emphasize practical realization, a model of an operating nuclear power plant is considered,with emphasis on the physical limitations imposed by the controller mechanism. It is shown, that despite wide variations in the model parameters as a function of the operating power level and of the temperature coefficient, the model can be updated on-line to a sufficient accuracy to produce negligible deviations between optimal model and suboptimal system performance. Apart from the realization of the adaptive controller, it is indicated that the proposed technique is also suitable for the fully computerized design of optimal and suboptimal feedback controllers for a wide variety of cost functions.

abstract: Thesis

abstract: Doctor of Philosophy (PhD)


title: Out-of-Plane Vibration of Portal Frames

contributor:
Heidebrecht, A.C.
Civil Engineering

abstract: Title: Out-of-Plane Vibration of Portal Frames, Author: Palamuthu Rengasami, Location: Thode

abstract: The theoretical and experimental investigations presented in this wrk are primarily related to the dynamic response of simple portal frames. the theoretical results obtained sing beam elements with consistent mass matrix, are compared with experimental results. The interaction of the components in modes of the combined structure is investigated.

abstract: Thesis

abstract: Master of Engineering (ME)


abstract: Title: Fundumental One-Dimensional Analysis of Photo-Diodes, Author: T.B. Remple, Location: Thode

abstract: the program developed by A.M. Start, in his paper, Fundamental One-Dimentional Analysis of Transistors, Philips Research Report Supplements, #4, 1976, has been modified to handle high voltage, reversed biased p-i-n photo-diodes. The physical involved in the development of stark;s model is summarized and three different p-i-n diodes are analyzed. A Schottky barrier is also analyzed by assuming the metal contact is a very highly doped semiconductor material. A listing of the program is given in the appendices, as well as a description of the program and a user's guide. Te program is written in Fortran, was run on a CDC 6400 in double precision (giving 29 digits accuracy), requiring 45 k of memory and 300 to 1000 seconds run time.

abstract: Thesis

abstract: Master of Engineering (ME)


contributor:
Bhaduri, R.K.
Physics

abstract: Title: Two-Pion Exchange Three-Body Force in Nuclear Matter, Author: Calk K. Ross, Location: Thode

abstract:
The two-pion exchange three-body nuclear force is discussed, and an effective two-body interaction derived which is capable of reproducing approximately its effect in nuclear matter. Treating the three-body interaction as a perturbation, the first order contribution to the binding energy of nuclear matter is derived using the actual three-body interaction, the effective interaction, and a recently suggested method in which the three-body effects are tarn approximately tint account by modifying the pion mass in the one-pion exchange potential. Although the latter method leads to a simple prescription for calculating the three-body effects hen no nucleon-nucleon cut-off is applied, the calculation is show to be considerably more difficult for the realistic case when a cut-off is applied, the calculation is shown to be considerably more difficult for the realistic case when a cut-off is introduced, and the modified pion mass is momentum dependent.

On the other hand, the effective interaction is found to reproduce quite well the actual three-body effects in first order. This fact is used as a basis for calculating the second order contribution using the effective interaction, and so an estimated of the three-body effects n nuclear matter is obtained. For a reasonable value of nucleon-nucleon cut-off, the three-body forces are shown to contribute approximately 6MeV additional binding to nuclei matter.

abstract: Thesis

abstract: Candidate in Philosophy


contributor:
Drysdale, R.G.
Civil Engineering

abstract: Title: The Study of Reinforced Concrete Columns in Existing Buildings, Author: D. Redekop, Location: Thode

abstract:
The purpose of this study was to gather data regarding the in-situ variability of parameters contributing to concrete column strength. Two parameters were studied variability of concrete strength and location of
longitudinal reinforcing bars in the columns .

It was found that concrete strength variability in the buildings lies within the ranges previously deduced by indirect methods, and that present field practice in
the placement of steel bars can, in certain cases, lead to small reductions in theoretical column strength .

abstract: Thesis

abstract: Master of Engineering (ME)


contributor:
Hoffman, T.W.
Chemical Engineering

abstract: Title: Heat Transfer to Sprays and Flowing Gases, Author: Kenneth G. Pollock, Location: Thode

abstract:
An experimental investigation of an Atomized Suspension Technique
system was carried out in an experimental apparatus of semi-pilot plant
scale. The complex gas flow patterns which occur in such systems as the
result of the interaction of natural convection and forced convection
prevented a quantitative analysis of the system.

The problem was then approached by dividing the overall process into
a number of idealized studies; these were convection in the entrance region,
radiation to a gas, radiation to a cloud of droplets.

A theoretical model was developed to predict heat-transfer rates
and gas temperature profiles in the entrance region (x/D < 2) of a
cylindrical coolumn. The model was verified experimentally.

A theoretical gas- radiation model was developed using the zoning
technique of Hottel. Experimental gas-temperature measurerrents qualitatively
verified the model.

An investigation of the established immersion cell technique for
the determination of drop-size distributions in sprays indicated that
this technique could not be used with any confidence in systems where
the spray is moving at low velocities.

Several experimental devices and techniques were developed
throughout the course of this study.

abstract: Thesis

abstract: Doctor of Philosophy (PhD)


title: The Structure of Asymmetric Graphs

contributor:
Sabidussi, G.
Mathematics

subject: structure, asymmetric, graphs, function, values

abstract: Extremal problems for asymmetric graphs and asymmetries of graphs are jointly investigated using function A(p,q). Values 0,1 of function are characterized.

abstract: Thesis

abstract: Master of Science (MSc)


title: Theoretical studies of unconventional superconductivity in Sr2RuO4

contributor:
Kallin, Catherine
Physics and Astronomy

subject:
unconventional superconductivity
Sr2RuO4
chiral superconductivity
chiral p-wave
edge current
topological superconductivity
multi-band superconductor
Leggett modes

abstract:
In this thesis we study the edge currents and the multi-band superconductivity in the unconventional superconductor Sr2RuO4.

Numerous measurements have given strong support for a topologically non-trivial time-reversal symmetry breaking chiral p-wave state in this material. However, the spontaneous edge current expected for this order has eluded experimental detection. In this thesis, we present a general theoretical description of the edge currents in chiral superconductors. Our results elucidate the connection between the edge currents and the topological property of the chiral pairing. On this basis, we argue that superconducting gap anisotropy, combined with surface disorder, may provide an explanation for the absence of observable edge currents in Sr2RuO4. In addition, contrary to intuitive expectations, the integrated edge current is found to identically vanish for any non-p-wave chiral superconductor in the continuum limit-- a result which may be connected with the orbital angular momentum problem in chiral superfluids, such as the A phase of He-3. In lattice models, the integrated edge current may not vanish in non-p-wave superconductors but, in general, is substantially smaller compared to that of a simple chiral p-wave.

In a separate study, we investigate the multi-band nature of the superconductivity in Sr2RuO4, via explicit microscopic calculations of the multi-band interactions. Our results indicate comparable pairing correlations on all of the bands and the existence of soft collective phase fluctuations--a Leggett mode. We also examine the possibility of alternative time-reversal symmetry breaking multi-band superconductivity which does not necessarily require chiral p-wave pairing.

abstract: Thesis

abstract: Doctor of Philosophy (PhD)


contributor:
Billigheimer, C.E.
Mathematics

abstract: Title: Integration and Laplace Transformation of Orthogonal Series, Author: Milos Novotny, Location: Thode

abstract:
In the first part of this thesis the basic
properties of classical orthogonal polynomials are derived from a unified
theory. Then sufficient conditions for term-by-term integration and
Laplace transformation of Fourier expansions in terms of an orthogonal
system with respect to a weight function on a bounded or unbounded interval
are given, and successively applied to Fourier expansions in terms of the
trigonometric system, the classical orthogonal polynomials, the Haar system
and eigenfunction expansions for ordinary linear differential equations with
boundary conditions on both ends of a compact interval as well as in limit
point and limit circle cases for an infinite interval. Finally a necessary
and sufficient condition for representation of a complex function as a
Laplace interval of f ε L(0,2π) with period 2π is proved.

abstract: Thesis

abstract: Doctor of Philosophy (PhD)


title: WEAR BEHAVIOUR OF COATED CARBIDE TOOLS DURING MACHINING OF Ti6Al4V AEROSPACE ALLOY

contributor:
Veldhuis, Stephen
Mechanical Engineering

abstract:
Titanium alloys are increasingly becoming the material of choice for a wide range of applications. They have found their way into aerospace, biomedical and automotive industries due to their superior properties such as good strength-to-weight ratio, high corrosion resistance and bio-compatibility. However, machining of titanium alloys has proven difficult over the years owing to several inherent properties of these materials. Titanium has a very strong chemical affinity and, therefore, has a tendency to weld or stick to the cutting tool during machining, which results in chipping and premature tool failure. Their low thermal conductivity causes high temperatures to be generated at the tool/workpiece interface, affecting tool life adversely. Additionally, their high strength at elevated temperature and low modulus of elasticity further impairs their machinability. Researchers have yet to find an effective strategy to overcome these challenges and improve the tool life during the machining of titanium alloys. The present research aims to find suitable tool coatings that will increase tool life during the machining Ti6Al4V, a prominent titanium alloy.
The alloy Ti6Al4V make up 60% of all titanium production [1]. Thus, the present research is focused on this alloy. Standard industrial practice for machining titanium alloys still revolves around the use of uncoated cemented carbide tools, although recently TiAlN coatings are being recommended by tool manufacturers. However, both uncoated and TiAlN coated cemented carbide tools have yet to achieve the desired tool life andproductivity. Hence, a variety of coatings have been investigated in this research study and are compared with uncoated and TiAlN coated carbide tools to find a more effective tool coating that will improve tool life during the machining of Ti6Al4V.
The coatings tested were chosen with the expectation that beneficial tribofilms could be generated on a tool’s surface due to the coatings’ self-adaptability characteristics under the cutting conditions experienced during machining. If the coating is properly engineered, these tribofilms have the potential to improve tool life significantly [2]. Experimental studies were carried out and the results showed that TiB2, CrN/WN and CrN/ZrN coated cemented carbide tools outperformed standard uncoated and TiAlN coated tools during Ti6Al4V machining. Detailed analysis of the best coatings revealed the beneficial tribofilms that each coating generated and how they affected tool wear.
Effect of deposition parameters on TiB2 (best coating) and chip breaker profile of the tools were also studied. Results showed that tools with positive chip breaker profile gave a better tool life and that low hardness TiB2 coating obtained through varying deposition parameters was more suitable for machining Ti6Al4V alloy compared to harder variants of TiB2 coating. End milling tests with TiB2 coated tools revealed that the coating was not as effective at increasing tool life as it was in turning.

abstract: Thesis

abstract: Master of Applied Science (MASc)


title: Lattice Basis Reduction Algorithms and the Subset Sum Problem

contributor:
Qiao, Sanzheng
Computing and Software

abstract:
It is well-known that the subset sum problem is NP-complete, which is the basis for the subset sum based public-key cryptosystems. Some attacks on such cryptosystems have been developed. Those methods reduce the subset sum problem to the problem of finding a shortest Euclidean-norm nonzero vector in a point lattice.

In this thesis, we propose a new hybrid lattice basis reduction algorithm by integrating the recent polynomial time Type-I reduction algorithm by Wen Zhang in 2015 with other techniques. We show that our algorithm is well suited for high dimensional lattices and apply it to the subset sum problem.
Our experiments demonstrate that our method can solve certain types of the subset sum problems with higher success rates than the most famous existing methods, the Lagarias-Odlyzko attack and the Radziszowski-Kreher attack.

abstract: Thesis

abstract: Master of Science (MSc)


contributor:
Dokainish, M.A.
Mechanical Engineering

abstract: Title: Vibration Analysis of Rotating Low Aspect Ratio Blades Idealized as Pretwisted Cantilever Plates, Author: Sunder Rawtani, Location: Thode

abstract: A method based on the finite element technique is developed for the vibration analysis of rotating and non rotating low aspect ratio turbo machinery blades. The blade is treated as an assembly of flat triangular elements. A partially conforming displacement function is used to obtain the bending stiffness matrix for an element. The accuracy of the method is tested by solving several plate and shell problems for which analytical or experimental results are available. The effect of pre twist, speed oration, disc radius and setting angle on the natural frequencies and the mode shapes is studied; by idealizing the blade as a pre twisted cantilever plate. An extensive review of different methods available for the vibration analysis of blades is also included.

abstract: Thesis

abstract: Doctor of Philosophy (PhD)


title: The Static and Dynamic Properties of Semicoherent Interfaces in Cu-Zn-Sn Alloys

contributor:
Purdy, G. R.
Metallurgy

subject: static, dynamic, properties, semicoherent interfaces, alloys, equilibrium

abstract:
 The equilibrium and kinetic properties of semicoherent interfaces between γ precipitates and β matrix in Cu-Zn-Sn are examined using a simple dislocation model. The predicted surface energies and mobilities are compared to those observed in experiments which also
assess the validity of current theories of interfacial stability in diffusion-controlled growth.

abstract: Thesis

abstract: Master of Science (MSc)


title: Characterization and Treatability Study of the Effluent from a Fish Processing Plant

contributor:
Murphy, K. L.
Chemical Engineering

subject: characterization, treatability, effluent, fish, processing plant

abstract:
 The wastewater from a freshwater fish processing plant was characterized. The plant processed perch and smelt, and thus the wastewater characterized was taken from the perch and smelt processing lines and a combined perch and smelt wastewater. The plant also manufactured fish meal from the fish offal. During this process the offal is pressed to obtain stickliquor. Since this stickliquor is a potential waste product it too was characterized.

 It was concluded that the wastewater was either of medium strength with large flows or of high strength with low flows.

 Batch and continuous reactor studies were undertaken to ascertain the degradability of the combined wastewater. It was determined that a reactor with either a detention in excess of 5 days with no sludge recycle or a short detention time reactor (7.5 hours) with sludge recycle would be necessary to effect maximum removal of total BOD5.

 The effect of physical treatment, flotation, sedimentation and in-plant screening, were also examined in a preliminary manner.

abstract: Thesis

abstract: Master of Engineering (MEngr)


title: TNF Alters Monocyte and Macrophage Phenotype and Function in Models of Chronic Inflammatory Disease

contributor: Medical Sciences (Molecular Virology and Immunology Program)

abstract: Aging is accompanied by increasing levels of pro-inflammatory cytokines, such as tumour necrosis factor (TNF), in the serum and tissues and changes in the phenotype and function of leukocytes. This “inflamm-aging” is known to contribute to numerous chronic diseases associated with aging and an increased susceptibility to infection. We hypothesized that age-associated increases in pro-inflammatory cytokines, TNF, contribute to monocyte and macrophage dysfunction, and ultimately, and an increased susceptibility to disease in the elderly and those with chronic inflammation. In this thesis, we conclude that TNF is a key mediator of age-associated inflammation, contributes to changes in inflammatory monocyte development, phenotype and function, and ultimately, impaired anti-pneumococcal immunity. We found that age-associated impairments in monocyte and macrophage function were influenced by the age of the host microenvironment, and not hematopoietic stem cells. Remarkably, exposure of aged immune cells to the microenvironment of a young host could reverse the detrimental effects of age and rescue monocyte and macrophage function. Moreover, in a model of diet-induced obesity, we demonstrated that inflammatory monocyte characteristics, which are regulated by TNF, could serve as a better predictor of insulin resistance in mice and humans than conventional biomarkers. Lastly, we demonstrate that TNF drives age-related defects in muscle function and mobility with age. Together, these studies increase the breadth of our understanding of the cross talk between inflammatory micro-environment and host immunity, and their impact on age-associated diseases. Although there are many more details to be unraveled, these studies indeed have made great progress and could be used to develop novel and much-needed therapeutic strategies to reduce the risk of infectious and chronic disease and improve the quality of life in the aging population.

abstract: Thesis

abstract: Master of Science (MSc)


title: COLCHICINE FOR PREVENTION OF PERIOPERATIVE ATRIAL FIBRILLATION IN PATIENTS UNDERGOING THORACIC SURGERY: PILOT STUDY

contributor:
Devereaux, P.J.
Bhandari, Mohit
Lamy, Andre
Health Research Methodology

abstract:
BACKGROUND:  Up to 20% of patients will develop postoperative atrial fibrillation (POAF) or atrial flutter after thoracic surgery.  These arrhythmias have been associated with serious complications such as death, stroke, and increased hospital length of stay.

OBJECTIVES:  This study aimed to determine: the feasibility of recruiting patients undergoing thoracic surgery to a randomized controlled trial (RCT) comparing colchicine and placebo for the prevention of POAF, the resources required to conduct a large trial, and compliance with the study drug.  The main efficacy outcome was POAF or atrial flutter within 30 days of randomization.

METHODS:  Patients aged 55 years and older undergoing a resection of tumor in the lung were recruited from two Canadian centers.  Participants were randomly assigned to receive colchicine 0.6mg or placebo orally within 4 hours before surgery.  Postoperatively, patients received colchicine 0.6mg or placebo twice daily for 10 days.  Troponin measurement and an electrocardiogram were performed daily during the first 3 days after surgery.  Patients’ follow-up occurred in hospital and at 30-days.

RESULTS:  One hundred patients were randomized (49 to colchicine and 51 to placebo) over a period of 12 months.  All patients completed the 30-day follow-up.  The mean staff time required to recruit and follow-up each patient was 165 minutes.  71% of patients completed the study drug course without interruption.  New POAF or atrial flutter occurred in 5 (10.2%) of the patients in the colchicine group and 7 (13.7%) of the patients in the placebo group (adjusted hazard ratio 0.69; 95% confidence interval, 0.20-2.34; p= 0.55).

CONCLUSION:  These results show the feasibility of COP-AF pilot study.  This pilot study will serve as the foundation for the large multicentre COP-AF RCT.

abstract: Thesis

abstract: Master of Science (MSc)

abstract: In patients undergoing thoracic surgery, as many as 1 in 5 patients will develop atrial fibrillation (fast disorganized chaotic heart beats).  This may lead to complications including death, stroke (clot in the brain), and longer hospital stay.  One theory is that atrial fibrillation is due to excessive inflammation in the body after surgery.  The purpose of this pilot study is to determine whether it is feasible to conduct a large study to test the effect of colchicine, an anti-inflammatory drug, on the risk of developing atrial fibrillation after thoracic surgery.  Participants were randomly assigned to take either colchicine or placebo starting on the day of the surgery for 10 consecutive days.  We documented the presence or absence of atrial fibrillation after surgery.  We demonstrated feasibility of enrolment, application of the intervention, and follow up of 100 participants.  The results of this study will be useful in developing a larger multicentre trial.


contributor:
Davies, J.A.
Geography

abstract: Title: Longwave Radiation Exchanges over Lake Ontario, Author: Peter J. Robinson, Location: Thode

abstract: The components of the radiation balance were measure over Lake Ontario for an 18 week period. Surface temperature and emissivity measurements were also made. Emissivity is constant, and outgoing longwave radiation can be determined from surface temperature alone. Water temperature changes appear o be greatly influenced by non-radioactive processes. The presence of flux divergence in the source layer is demonstrated. Incoming longwave radiation various rapidly in cloudless conditions. In addition, it is greatly influenced by low and medium cloud.. The relationship between net shortwave radiation and net radiation is analysed for varying time periods, and reason for the variable relationship are advanced. Several empirical methods for predicting net radiation or its components were tested, with variable results.

abstract: Thesis

abstract: Doctor of Philosophy (PhD)


title: An Investigation of the Crystal Structures of α and β-Cu2P2O7

contributor:
Calvo, C.
Physics

subject: crystal structures, polymorph, lattice

abstract:
 A high temperature polymorph of α-Cu2P2O7 was found above 70°C.
The lattice parameters and space groups of both phases were determined
from X-ray photographs. The crystal structures of α and β-Cu2P2O7 were
refined by crystallographic least squares analysis and the molecular
geometry obtained was compared with that of other closely related compounds of the transition metal ion pyrophosphate series. The central oxygen atom was found to have enhanced thermal motion or disorder in agreement with I.R. spectroscopic studies of Lazarev. The bond lengths obtained for the P2O7^4- ion were discussed in reference to values predicted by Cruickshank. Evidence of a Jahn-Teller effect was found in the case of the Cu++ ion. A description is given of a relatively efficient method
of measuring intensities of Bragg reflections, using a single crystal
diffractometer.

abstract: Thesis

abstract: Master of Science (MSc)


contributor:
Bandler, J.W.
Electrical Engineering

abstract: Title: General Programs for Least pth and Near Minimax Approximation, Author: Jadranka K. Rizoniko-Popovic, Location: Thode

abstract: User-oriented computer programs in FORTRAN IV for discrete least pth approximation with a single specified function, and more generalized discrete least pth approximation with various specifications, which may also be used for nonlinear programming, are presented. Values of p up to 10^6 can be used successfully in conjunction with efficient gradient minimization algorithms such as the Fletcher-Powell method and a recent method due to Fletcher. It has already been demonstrated how efficiently extremely near minimax results can be achieved on a discrete set of sample points using this approach and the programs written verify this. The programs may be applied to a wide variety of design problems with a wide range of specifications. They are suitable for electrical network and system design and such problems as filter design.

abstract: Thesis

abstract: Master of Engineering (ME)


title: Forsteritic Determination of Olivine by XRD Analysis

contributor:
McNutt, R. H.
Grundy, H. D.
Geology

subject: forsteritic, olivine, XRD analysis, lattice

abstract:
 Fo. determinative curves for lattice planes (301), (311), and (401) were calculated from four natural olivines. 2θ values for each olivine were computed from the lattice parameters using the reciprocal lattice d* for the orthorhombic crystal system d*hkl = [h^2/a^2 + k^2/b^2 + l^2/c^2]^1/2 combined with the Bragg equation λCuKα = 2 sin θhk / d*hkl

 XRD patterns for 10 natural olivines were used to determine their respective Fo. composition. Errors were calculated for the Fo. composition of the natural olivines yielding an accuracy from the determinative curves of± 6 wt. % Fo. An olivine of 90 wt. % Fo. was
X-rayed and plotted along the determinative curves giving values of Fo.
composition for (301), (311) and (401) of 89, 87 and 85 wt. % respectively.

  The effect of Ni, Mn and Ca substituting into the (Mg, Fe) olivine structure causing Δ2θ shifts was also considered and found to be negligible for natural (Mg, Fe) olivines.

abstract: Thesis

abstract: Bachelor of Science (BSc)


abstract: Title: An Investigation of the Crystal Structure and Phase Transformations of Cu and Zn Pyrophosphate, Author: Beverly E. Robertson, Location: Thode

abstract: <p>The crystal structures of the high temperature phase of Cu2P2O7 has been refined by the method of least squares. The structure of the low temperature from was refined using both of the allowed space groups and the centric space group C2/c is preferred. Diffuse streaks which were found to be associated with the phase transformation were analyzed and used to construct a pseudo one dimensional order-disorder model for the mechanism of the phase transformation. Also the lattice parameters of α-Zn2P2O7 have been measured and the structure has been refined using the non-centric space group Ic.

abstract: Thesis

abstract: Doctor of Philosophy (PhD)


title: The Measure Algebra of a Locally Compact Group

contributor:
Husain, T.
Mathematics

subject: measure, algebra, locally compact, group

abstract:
 Let G be a locally compact group (= locally compact Hausdorff topological group). By the measure algebra of G we mean the Banach *-algebra M(G) of bounded regular Borel measures on G. The major results of this work are a structure theorem for norm decreasing isomorphisms of measure algebras, and a characterization of those Banach algebras which are isometric and isomorphic to the measure algebra of some locally
compact group. We also obtain some results on subalgebras of
M(G) and on representations of G.

abstract: Thesis

abstract: Doctor of Philosophy (PhD)


title: Velocity Profiles in Annular Passages

contributor:
Wade, J.H.T.
Mechanical Engineering

abstract: Title: Velocity Profiles of Annular Passages, Author: Thomas W. Ricker, Location: Thode

abstract:
An experimental study of turbulent velocity profiles of water flowing in a vertical annular passage is reported in this thesis. Presented are profiles for eccentricities ranging from 0% to 80% and Reynolds numbers from 40,000 to 104,000 in an annulus having a 0.286 radius ratio.

Velocities were measured along five radii for all but the concentric configuration and the two arbitrarily chosen configurations are represented in the form of cross-sectional maps of the isovels. A method for deriving the powers N1 and N2 as defined by the equations u/um = [(r2-r)/(r2-rm)]^N2 and u/um = [(r-r1)/(rm-r1)]^N1 is suggested, and these powers were found for the two configurations investigated.

abstract: Thesis

abstract: Master of Engineering (ME)


contributor:
Oravas, G.E.
Civil Engineering

abstract: Title: Stress and Strain in a Shallow Elastic Calotte Shell, Author: Glenn Riley, Location: Thode

abstract: This thesis describes the experimental and theoretical analysis of a shallow spherical calotte shell of hexagonal plan. Installation of strain agues in the circumferential ad radial directions enabled the measurement of the direct and flexural strains, from which the corresponding stress resultants and stress couples could be evaluated. In the theoretical analysis, an approximate solution utilizing the collocation procedure for satisfaction of boundary conditions is used.

abstract: Thesis

abstract: Master of Engineering (ME)


title: Grain Orientation of Massive Sandstones

contributor:
Walker, R. G.
Geology

subject: grain, orientation,massive sandstones, sediment, concentration, deposition

abstract:
 This study describes the analysis of orientation of elongate quartz grains in massive turbidite sandstones from the Chetco Formation (Jurassic) of southwestern Oregon. Inferences on depositional fabric of this resedimented facies are made.

 Grain orientation in the plane parallel to bedding is generally not highly significant statistically, and current direction,
supplied by imbrication, is not persistent vertically through the beds. However, a rotation pattern of current direction in each bed is detected.

 Variations in orientation distribution could represent variations in sediment concentration of the flow and in the rate of
deposition.

abstract: Thesis

abstract: Bachelor of Science (BSc)


contributor:
Kardos, G.
Mechanical Design

abstract: Title: An Introduction to the Analyis of Fibre Reinforced Composite Structures, Author: Brian E. Risenborough, Location: Thode

abstract:
Prevailing approaches to the analysis of laminated composite structures are reviewed and serious shortcomings are noted in each. A promising new, more rational method, founded upon the recently developed theory of limited opposites, is described and equations of laminate behaviour are established in accordance with the theory.

The new method is employed in the analysis of a fibre-reinforced cylindrical storage tank and a new equations of deflection, applicable for both laminated orthotropic and isotropic materials of construction, is derived. A computer program, based upon this analysis, and capable of performing a complete stress analysis at any point in the tank, is included.

Results of a series of parametric studies, relative to the construction of filament wound storage tanks, are reported and new design guidelines are suggested.

abstract: Thesis

abstract: Master of Engineering (ME)


title: The Effect of Meteorology on Atmospheric Particulate Concentrations in Hamilton, Ontario

contributor:
Eyles, Carolyn
McCann, S. Brian
Geography

subject: meteorology, atmospheric particulate, concentrations, air pollution

abstract:
 Ambient air pollution and pollution emitted from point sources, contribute to the total suspended particulate loadings measured at various monitoring stations, in any given area. Studies have shown that various meteorological variables may influence the concentration of particulates measured at these stations. 1989 data, from monitoring stations throughout Hamilton, Ontario, in conjunction with meteorological data from the Mount Hope airport, have been used to reveal, and to explain the aforementioned relationships. Results from graphical analysis, supports past findinqs from Stewart and Matheson (1967), Rouse and McCutcheon (1970), Dobroff (1990) and others, by showing that winds derived from a northern sector increase mean particulate loadings, and that wind speeds tend to be inversely related to measured particulate concentrations. In contrast to supporting findings from the graphical
analysis, statistical ordinary least squares regression showed that for more stations than not, most parameter coefficients were not statistically significant. Results from the coefficient of determination show that none of regressions employed (linear, linear-log and log-log) could
explain the relationship between the independent meteorological variables and the dependent variable (particulate concentration at a given monitoring site) with great precision. It follows that a non-linear correlation may well explain the dependence of particulate loading on wind speed, wind direction, mean temperature and total precipitation, and that source, (point and fugitive emissions), and other factors play important roles in this complex relationship.

abstract: Thesis

abstract: Candidate in Philosophy


contributor:
Harms, A.A.
Engineering Physics

abstract: Title: Physics Aspects of a CANDU Nucler Reactor, Author: Marc Roberge, Location: Thode

abstract:
Certain scientific-technical aspects of the CANDU nuclear energy system are discussed. Major emphasis is placed on the fuel cycle, thorium breeding, heat and mass transfer, safety, and environmental impact.

The analysis is based on a critical review of the published literature. Both qualitative and quantitative aspects are discussed and subsequently summarized.

abstract: Thesis

abstract: Master of Engineering (ME)


title: X-Ray Emission Analysis Using Radioisotopic Alpha-Particle Excitation

contributor:
Fritze, K.
Chemistry

subject: x-ray, emission, radioisotopic, alpha-particle, excitation

abstract:
 The combined capabilities of alpha-particle emitting isotopic excitation sources and modern semiconductor detectors are investigated with a view to extending the light-element range of radioisotope-based X-ray emission analysis.

 The construction and performance of a windowless low-energy X-ray spectrometer designed around a lithium-drifted
silicon detector and a 210Po source are discussed. It is shown that under the conditions used low-energy X-ray emission and detection are greatly favoured.

 Measurements of relative cross-sections for the production of X-rays by ~5.2 MeV alpha-particles in elements
from oxygen to iron are reported. The results for elements of Z>16 are in good agreement with those predicted from the scaling of equal velocity proton values but show large positive
deviations for elements of Z<16.

 Investigative applications of the spectrometer to
quantitative analyses of blast-furnace slags, iron ores and silicate rocks for oxygen, silicon, sulpher, calcium and iron are described.

 The future prospects of radioisotopic alpha-particle X-ray excitation methods are surveyed.

abstract: Thesis

abstract: Doctor of Philosophy (PhD)


abstract: Title: The Construction and Operation of a Thermal Diffusion Column, Author: David L. Prosser, Location: Thode

abstract: The first observation of the phenomenon of thermal diffusion was made by Soret in 1878. He found that a concentration gradate was set up in a liquid solution when a temperature gradient existed in the solution. Hence the lighter molecules or ions in the solution moved toward the hotter part of the solution faster than the heavier particles, which distributed the homogeneity of the solution. Two gases or gaseous isotopes were separated in the same way by a temperature gradient. A rigorous mathematical and theoretical treatment was given to thermal diffusion by Enskog in 1911, and independently by Chapman in England in 1917. In 1918 first experimental data was obtained by Chapman and Dootson. Mullikan discussed the use of the thermal diffusion process for the separation of gaseous isotopes, but concluded that other methods at that time superior. However, he did not consider the new twist given to the application of thermal diffusion by Clusius and Dickle which consisted of thermal diffusion in conjunction with convection currents which increased the effect of thermal diffusion enormously. In order to produce this effect, they used a specially designed column consisting of two concentric tubes mounted vertically, the inner one of which was a hot wall and the outer one a cold wall. A temperature gradient was set up radially from the cold wall to the hot wall. Then the convection currents carried the light molecules, concentrating at the hot wall, up the tube and brought the heavier molecules, at the cold wall, down the cold wall. This effect is sometimes called thermal syphoning. The separated stab;e isotopes of hydrogen, carbon, nitrogen, oxygen and sulphur, are of considerable importance in isotope exchange and trace work. These isotopes can be separated with relative ease by chemical exchange methods which are particularly suited for the production of relatively large amounts of material at medium concentrations. The thermal diffusion the mod, on the other hand, the method first used by Clusius and Dickel, is one of the best methods for producing small quantities of highly enriched isotopes. It would be most economical, therefore, to concentrate those isotopes by chemical exchange in a first stage in order to produce the large quantities of enriched material at medium concentrations, which will be required for he most chemical and medical tracer work, and to enrich a much smaller amount of material still further by a second stage thermal diffusion unit for the few experiments where very high concentrations are desirable or necessary. High concentrations of the isotopes will be required in experiments where high dilution of the "tagged" material is encountered and for experiments designed to study the physical and chemical properties of the separated isotopes. Thermal diffusion columns have been set up at McMaster University to make possible the further enrichment of the isotope which have already been concentrated by chemical exchange methods. Several years ago the heavy isotopes of oxygen and sulphur were separated in this laboratory in distillation and chemical exchange methods, respectively. The latter involved the exchange between sulphur dioxide and bisulphite ion in solutions. Our thermal diffusion columns will be used first to further enrich O^18 samples now on hand. Of the elements mentioned above, deuterium has been an article of commerce for some time, and 775 percent N^15 produced by chemical methods is now on the market. In the latter car, it might be of interest to produce a small quantity of high concentrations. Further, the Houdry Catalytic Corporation has plans to produce O^13 at two concentrations, twelve percent and sixty percent, in a two stage system, the latter stage being a thermal diffusion unit. Here again there may be experiments where high concentrations are desirable. At the present time, however, the isotopes of oxygen and sulphur are not available commercially, but can be procured from several universities (McMaster) only at low concentrations. Four thermal diffusion units have been completed. One of there units has already been tested on the separation of the nitrogen gas as a working substance. The results are not most encouraging and incite an enrichments factor of seven for the nitrogen isotopes using four units or 36 feet of column. Details of the thermal diffusion column and of the test runs made with one unit are discussed below.

abstract: Thesis

abstract: Master of Science (MS)


title: Huntingtin N17 Domain is a Reactive Oxygen Species Sensor Regulating Huntingtin Phosphorylation and Localization

contributor:
Truant, Ray
Biochemistry and Biomedical Sciences

subject:
Huntingtin
Oxidation
Huntington's Disease
Phosphorylation
Cell Stress

abstract: The huntingtin N17 domain is the master regulator of huntingtin intracellular localization. N17 is post-translationally modified, and phosphorylation of N17 serines 13 and 16 facilitate the stress dependent nuclear translocation of huntingtin by inhibiting CRM1 binding and nuclear export. In Huntington’s disease (HD), mutant huntingtin is hypo-phosphorylated and increasing N17 phosphorylation has been shown to be protective in HD mouse models. N17 phosphorylation is therefore a valid therapeutic sub-target of huntingtin. The ER stresses that have been previously characterized to affect huntingtin phosphorylation are broad, likely activating a plethora of response pathways. Thus, in this study, we sought to define a specific stress that could affect huntingtin phosphorylation and nuclear localization. Here we show that huntingtin localization and phosphorylation can be specifically affected by reactive oxygen species (ROS). We identify a highly conserved methionine at position 8 (M8) as the specific sensor of oxidative species within N17 and show the capacity of oxido-mimetic M8 point mutations to affect N17 structure, localization and phosphorylation. We also define a specific molecular mechanism whereby N17 oxidation promotes membrane dissociation, thus increasing kinase accessibility and subsequent phosphorylation. These results define a precise molecular mechanism for the normal biological regulation of huntingtin phosphorylation by oxidative signalling. This ability of huntingtin to sense ROS levels at the ER provides a link between age-associated stress and altered huntingtin function. It suggests that ROS stress due to aging may be a critical molecular trigger of HD that could explain the age-onset nature of disease.

abstract: Thesis

abstract: Master of Science (MSc)


title: Galois Theory and its Application to the Problem of Solvability by Radicals of an Equation Over a Field of Prime or Zero Characteristic

contributor:
Lane, N. D.
Mathematics

subject: Galois Theory, solvability, radicals, equation, field, prime zero, characteristic

abstract:
In Part I of the thesis an account is given of the basic algebra of extension fields which is required for the understanding of Galois theory. The fundamental theorem states the relationships of the subgroups of a permutation group of the root field of an equation to the subfields which are left invariant by these subgroups. Extensions of the basic theorem
conclude Part I. In part II the solvability of equations by radicals is discussed, for fields of characteristic zero. A discussion of finite fields and primitive roots leads to a criterion for the solvability by radicals of equations over fields of prime characteristic. Finally, a method for determining the Galois group of any equation is discussed. Most of the material in the introductory chapters is taken from Artin's: Galois Theory (cf. p. 120).

abstract: Thesis

abstract: Master of Arts (MA)


title: Characterization of Residual Organics from Biological Treatment

contributor:
Murphy, K. L.
Chemical Engineering

subject: characterization, residual organics, biological treatment, gel filtration, molecular

abstract:
 Gel filtration chromatography on Sephadex gels G15 and G50, was used to characterize the residual organic materials found in effluents from biological treatment. Molecular weight distributions were determined as the equivalent molecular weight distribution of a homologous series of sugars and alcohols. The homologous series was also used to determine
equivalent molecular radii, based on Corey-Pauling-Koltun space filling models of the homolgous series.

 To determine the distributions of residual organics from mixed cultures grown on simple, pure substrates, laboratory batch studies were performed. For this purpose, media containing glucose or glutamic acid substrates and a bicarbonate-phosphate
buffer system were innoculated with activated sludge. Both high and low substrate and microorganism concentrations were used at constant temperature and pH. As a comparison for the mixed cultures, a representative strain of Flavobacterium sp. isolated from activated sludge was grown in pure culture on glucose.

 Both the laboratory mixed culture effluents and treatment plant effluents contained material of equivalent molecular weight less than 1500. However, little similarity appeared to exist between the low molecular weight (<1500) distributions of treatment plant effluents and those from the mixed cultures. A significant fraction of the treatment plant and batch effluents had equivalent molecular weights of greater than 10,000. The pure culture studies showed that a single strain of bacteria can produce material of equivalent molecular weight both greater and less than 1500.

abstract: Thesis

abstract: Master of Engineering (MEngr)


title: Elasto-capillary deformation of films and rods

abstract: Elasto-capillarity is the ability of capillary forces to deform elastic structures. This phenomenon is found at all length scales and is central to natural phenomena such as the coalescence of wet hairs as well as technological applications like microfluidics and microelectromechanical systems. In this thesis we investigate some of the most fundamental examples of elasto-capillarity -- the deformation of thin films and rods by liquid drops and bubbles. Through novel experiment techniques we are able to accurately predict the shape of elastic deformations in compliant polymer films as a function of tension in the film due to capillary forces from liquid drops. We are also able to accurately predict the onset of winding of slender polymer rods around liquid bubbles.

abstract: Thesis

abstract: Master of Science (MSc)


title: The Effects of Gas Composition, Gas Flow Rate and Reaction Temperature on the Reduction Behaviour of Fixed Beds of Hematite Pellets

contributor:
Lu, W.-K.
Metallurgy

subject: gas composition, gas flow rate, reaction, temperature, fixed beds, Hematite Pellets

abstract: An Experimental investigation has been conducted to determine the effects on degree of reduction and efficiency of utilization of gases of changes in the levels of several variables when reducing fixed beds of commercial hematite pellets. The effects on reduction behaviour of changes in the levels of reducing gas composition and flow rate, and reaction temperature, were determined by graphical and numerical techniques.

abstract: Thesis

abstract: Master of Engineering (MEngr)


abstract: Title: Local Experiences of Cooperative Formation: A Hamilton Case Study, Author: Stephen Robichaud, Location: Thode

abstract: By examining the local experiences of one of Hamilton's housing cooperatives, this research paper analyzes and explains the actions of those who were involved with the cooperative and shows two main aspects of the cooperative. First, in forming and locating the cooperative, an opposition minimizing strategy was employed to minimize external opposition to the cooperative. Second, problems experienced in program delivery were found to have a detrimental effect upon the members of the cooperative, problems that need to be addressed to ensure the survival of the cooperative.

abstract: Thesis

abstract: Bachelor of Arts (BA)


title: Change of Rings Theorems

contributor:
Mueller, B.J.
Mathematics

abstract: Title: Change of Rings Theorem, Author: Philip M. Robinson, Location: Thode

abstract:
The intention of this thesis is
to gather together the results of various papers
concerning the three change of rings theorems,
generalizing them where possible, and to determine
if the various results, although under different
hypotheses, are in fact, distinct.

abstract: Thesis

abstract: Master of Science (MS)


contributor:
Ritchie, I.G.
Engineering Physics

abstract: Title: Internal Friction in The Region of The Grain Boundary Peaks in Pure Zirconium and Dilute Zirconium Alloys, Author: R.C. Robinson, Location: Thode

abstract:
Internal friction, in the region of the
grain boundary peaks, has been examined in nominally
pure zirconium and dilute zirconium alloys. Experimental
observations were made using both torsion and
reed internal friction pendulums. The effect of various
heat treatments on the peaks were investigated. Strain
amplitude dependent damping in the region of the Low
Temperature Peak was observed. A qualitative model
is presented to explain the experimental observations.

abstract: Thesis

abstract: Master of Engineering (ME)


contributor:
Robinson, J.E.
Engineering Physics

abstract: Title: The Development and Use of an Internal Friction Technique for the Study of Radiation Damage, Author: R. C. Robinson, Location: Thode

abstract:
The use of internal friction methods in the
study of radiation damage is briefly reviewed. The
development of an internal friction technique utilizing
a noncontacting optical transducer for detection of
flexural resonant vibrations in a cantilever beam is
described. An account of some preliminary experiments
is given, including examination of the Snoek peak and
the strain amplitude dependence of internal friction
in iron and niobium. Damping measurements were made
in the free-decay mode.

abstract: Thesis

abstract: Master of Engineering (ME)


contributor:
Baird, M. H. I.
Engineering Physics

abstract: Title: Mixing Effects and Hydrodynamics of Vortex Rings, Author: Anil Rohatgi, Location: Thode

abstract:
Vortex rings are considered a promising means of
mixing stratified fluids, e.g. in the blending of oils and
the destabilisation of thermocline in harbours and lakes. In
the presence of pollutants, a thermocline causes a deterioration
in water quality and produces environmental problems .

The first two chapters discuss the history of vortex
rings and the experimental procedures used to obtain stratification of fluids in a laboratory tank . Chapter 3 describes the
energy relationships of vortex rings and provides an expression
for the minimum potential energy required to mix a given stratified
fluid. The results are given in Chapter 4 and the energy
and volumetric efficiencies are discussed in Chapter 5.

Generation of large and powerful rings for industrial
mixing purposes is discussed in Chapter 6 , the hydrodynamic
testing of these rings produced at a 25.4 cm orifice is discussed
in Chapter 8. The conclusions from both the laboratory mixing
tests and the hydrodynamic testing of large rings are given
in Chapter 9.

abstract: Thesis

abstract: Master of Engineering (ME)


title: EFFECTS OF PROCESS CONDITIONS ON POLYMER NETWORK FORMATION: APPLICATION IN PARTICLE COATING AND MODELING USING MOLECULAR DYNAMICS

contributor:
Xi, Li
Chemical Engineering

subject:
Polymer Network
Surface Coating
Molecular Modeling

abstract:
Cross-linked polymers are of great importance to industrial practice and theoretical studies. The unique network structures of these materials have endowed them with many superior properties. In this thesis, we study cross-linked polymers from both of experimental and theoretical sides, with an emphasis on the formation process and properties of the prepared networks. Two specific problems are investigated: development of polymer coatings over solid particles with in situ curing, and molecular dynamics (MD) study of network formation kinetics and structure-property relationship.
In the study of polymer coating, a hot-melt coating process for solid particles is developed. Phenolic resin is used to coat the substrates and subsequently cured in situ. Among various processing parameters, temperature is found to play an especially important role in the coating performance. Higher temperature leads to stronger coating layers with better barrier properties, whereas lower temperature is preferable for better surface morphology. These two trends can be partially reconciled with ramping temperature profiles; however, the improvement is eventually limited by the rate of heat transfer.
In MD study, the effects of precursor topology on the formation, structure and mechanical properties of polymer networks are studied. Cross-linked polymer networks are synthesized from three sets of precursors with varying chain length. Little difference is observed between these networks in typical properties including radial distribution function, overall statistics of network connectivity, and glass transition behaviors. The elastic modulus of the network is found to correlate strongly with the number of elastic strands in the network, except at the highly-cross-linked limit where substantial discrepancy is observed between networks from different precursors. Although these final networks contain a similar level of structural defects, the choice of precursor has a significant effect on the spatial distribution of the defects, which explains the precursor dependence of their mechanical property observed in the tensile test.

abstract: Thesis

abstract: Master of Applied Science (MASc)


title: Toward the Industrial Application of a Solid-Oxide Fuel Cell Power Plant with Compressed Air Energy Storage

title: Design, Simulation, Optimization, Techno-Economic Analyses and Life-Cycle Analyses of Solid-Oxide Fuel Cell Power Plants

contributor:
Adams, Thomas A.
Chemical Engineering

subject:
Solid-Oxide Fuel Cells
Carbon Capture
Peaking Power
Compressed Air Energy Storage
Optimization
Natural Gas
Coal
Life-Cycle Analysis
Simulation
Clean Energy

abstract:
The global electricity generation industry is very reliant on the use of fossil fuels, particularly natural gas and coal. However, it is quickly becoming a reality that the over-consumption of these resources will continue to lead to significant global damage via global warming, ecosystem destruction, and the depletion of these so-called non-renewable re-sources. To combat this issue, renewable sources such as wind, biofuels and solar are be-coming much more prevalent in the power generation industry, but significant economic, reliability and availability barriers to entry will prevent these sources from being major contributors to the power industry for decades.
To this end, this thesis focuses on the design, operation, optimization and life cycle analysis of an integrated solid-oxide fuel (SOFC) cell power plant integrated with com-pressed air energy storage (CAES). This plant, fueled by either natural gas or coal, can make much more efficient use of their limited non-renewable fuel sources, and are capable of achieving nearly 100% carbon capture at the plant boundary. This plant is intended to serve as a more efficient and environmentally responsible alternative to current power generation methods while still exploiting remaining fossil fuels to their fullest extent.
This thesis details the design, sizing and simulation of integrated SOFC/CAES plants in Aspen Plus so that full feasibility and techno-economic analyses may be performed, the results of which are then compared to the current state-of-the-art (SOTA) options. In order to compare the plants on an environmental level, full cradle-to-grave life-cycle analyses using the ReCiPe 2008 method are completed for each SOFC-based plant and all comparable SOTA options under a wide range of assumptions and plant configurations, such as the use of carbon capture strategies. Furthermore, detailed reduced-order dynamic models of the integrated SOFC/CAES plants are developed and simulated with a newly developed rolling-horizon optimization method to assess the load-following capabilities of the integrated plant. Real scaled demand data for the market of Ontario, Canada for the years 2013 and 2014 are used as the demand data for the simulations.
This thesis takes strides in proving the feasibility of an integrated SOFC/CAES power plant for providing clean, efficient, reliable and cost-effective power using fossil fuels. The next steps for this project involve the development of a lab-scale pilot plant, which would be used to validate simulation results and provide an opportunity for the real-time application and assessment of the potential of this plant design.

abstract: Thesis

abstract: Doctor of Philosophy (PhD)


title: A Parallel Computing System

contributor:
Della Torre, E.
Electrical Engineering

subject: parallel, computing, system, array, cells, matrix

abstract:
 A highly parallel computing system capable of computing transcendental functions, matrix operations and iterative calculations has been devised and a typical cell has been
implemented. The system consists of an array of cells, a control unit, a PDP-11 computer and an interface unit. The array uses modified SOLOMON type of communication between cells. Each cell consists of 15 words and arithmetic hardware. Arithmetic and logic operations, on words or bytes, may be performed serially between pairs of these words. Division and floating-point arithmetic are under software control. Parallel algorithms have been developed. A set of instructions and mnemonics permits a practical use of the system. The possibility of using the array as an associative-memory processor is also considered. The system has been tested by using the software package prepared. Although only one cell has actually been constructed a complete array has been simulated on a PDP-11 computer.

abstract: Thesis

abstract: Master of Engineering (MEngr)


contributor:
Wood, Derick
Mathematics

abstract: Title: Restricted Parallelism and Regular Grammars, Author: Robert D. Rosebrugh, Location: Thode

abstract: This thesis studies the properties of k-parallel right-linear languages. An infinite hierarchy of language families is found and closure properties of these families are studied. The language families are characterised in terms of simple languages and non-deterministic generalised sequential machine mappings. In addition a characterisation of k-right-linear simple matrix languages by k-parallel right-linear languages with a control device is given.

abstract: Thesis

abstract: Master of Science (MS)


title: Hybrid Foamed Co-Injection Molding

contributor:
Thompson, Michael
Hrymak, Andrew
Chemical Engineering

abstract: Title: Hybrid Foamed Co-Injection Molding, Author: Karen Rogers, Location: Thode

abstract:
This project examines the co-injection molding of a TPO material, using a solid skin, and a microcellular core material. For useful industry applications, the density, and the tensile and flexural mechanical properties were examined, and compared to a solid injection molded TPO plaque achieve using different processing parameters and materials. Correspondingly, the foam structure was examined to determine structural effects on the final mechanical properties. It was discovered that density can be reduced by as much as 32.0% ±0.8%, while still maintaining mechanical properties comparable to those of a similar part using a solid material for the core. Elliptical cellular shapes and cells distributed more widely in the gap direction corresponded with lower density parts, yet maintained mechanical properties similar to higher density foams with circular cells concentrated along the center of the gap direction.

Fracture initiation was examined to determine if failure occurred within the foam structure of the parts, or the foam/core interface. Observations indicate that failure depended on the type of force applied to the part, as well as the material used to form the part itself.

abstract: Thesis

abstract: Master of Applied Science (MASc)


title: Detection of Short CO2 Pulses

contributor:
Garside, B.
Alcock, J.
Engineering Physics

abstract: Title: Detection of Short CO2 Pulses, Author: Daniel F. Rollin, Location: Thode

abstract: A passively mode-locked multi-atmosphere CO2 laser was used to produce sub-nanosecond pulses. After up-conversion of the 10.6 um radiation in a proustite crystal detction was done with a streak camera-optical multichannel analyser combination. Pulses shorter than 100 psec (FWHM) were recorded.

abstract: Thesis

abstract: Master of Engineering (ME)


title: Investigating the Role of the NLRP3 Inflammasome in Statin-Induced Myopathy

title: The NLRP3 Inflammasome Contributes to Statin Myopathy

contributor: Medical Sciences (Cell Biology and Metabolism)

subject: Inflammasome Statins Myopathy Prenylation Caspase-1 Atrogenes

abstract: As a front-line treatment for cardiovascular disease, statins are among some of the most widely prescribed drugs worldwide. Statins are effective at lowering cholesterol, but approximately 7-29% of patients report some form of adverse muscle effect during the course of treatment. The severity of these side effects ranges from low-level to life-threatening myopathy. The mechanism of statin myopathy remains ill-defined, but muscle-specific E3 ubiquitin ligases have been implicated. In addition, statins have been shown to activate caspase-1 (and increase IL-1β) in immune cells, which is a key effector of the NLRP3 inflammasome. The relevance of this inflammatory response in statin myopathy remains unknown. Using C2C12 myotubes, an in vitro model of statin-induced myopathy was developed to test the impact of NLRP3 inflammasome activation on markers of statin myopathy. Gene expression of the muscle-specific E3 ubiquitin ligases atrogin-1 and MuRF-1 (atrogenes) were used as markers of statin-induced myopathy. Lipopolysaccharide priming of the NLRP3 inflammasome was found to lower the effective dose of fluvastatin required to augment atrogene expression. This effect correlated with reduced phosphorylation of Akt and FOXO3a, a transcription factor regulating atrogene expression. Statin-induced atrogene expression was also found to be dependent on an isoprenoid that is required for protein prenylation rather than cholesterol biosynthesis pathways.  Fluvastatin increased caspase-1 activity in a prenylation-dependent manner and selective inhibitors of NLRP3 and caspase-1 were able to prevent increased atrogene expression with fluvastatin treatment. Therefore, the NLRP3 inflammasome contributes to markers of statin-induced myopathy through a prenylation-dependant pathway in muscle cells. This work presents a novel mechanism involved in statin myopathy, and has shown that the inflammasome may represent a new drug target to mitigate muscle symptoms in patients taking statins.

abstract: Thesis

abstract: Master of Science (MSc)

abstract: Statins are a class of widely prescribed cholesterol-lowering drugs that reduce the risk of heart attack and stroke. However, many patients often complain of statin-induced muscle side effects (myopathy) that impact their quality of life. Symptoms of this statin-induced myopathy can manifest as muscle pain and weakness. The underlying biology causing this condition is still not well understood. Independent of its cholesterol-lowering effect, statins can activate an immune receptor called the NLRP3 inflammasome, indicating that inflammation may contribute to myopathy. Therefore, the primary goal of this study was to determine if this immune response contributes to statin-induced myopathy. It was found that inhibition of the NLRP3 inflammasome lowers markers of statin myopathy. Results from this study will provide further insight into mechanisms regulating this myopathy, and may lead to new treatments that can help alleviate statin side effects in muscle.


contributor:
Takahashi, I.
Biology

abstract: Title: An Investigation of the Genetics of Sporulation in Bacillus subtilis, Author: Robert G. Roy, Location: Thode

abstract: The investigation was carried out in order to eliminate a hypothetical sporulation factor from wild-type strains of Bacillus subtilis using agents know to remove episomes. The subsequent investigations produced no mutants with properties predicted for strains missing the sporulation factor. When cells were exposed to UV light prior to treatment with acridine dyes there was, however, a significant increase in the production of normal sporulation mutants.

abstract: Thesis

abstract: Master of Science (MS)


title: A Model to Provide a Measure of Agricultural Productivity Using Remote Sensing Techniques

contributor:
Wood, H. A.
Geography

subject: agricultural, productivity, remote sensing techniques, farm, cattle

abstract: This thesis provides a means of measuring the type and number of livestock on a given farm in southern Ontario using as a data base aerial photographs of medium scale. The feasibility of making such measurements is shown to be an extension of past work in the field of agricultural air photo interpretation. The methodology is presented in the form of a model. The inputs from aerial photographs are crop acreages, building type and dimensions, and silo sizes. Average yields in each study area, in combination with crop acreage gives feed available. A comparison is made between feed weight and housing space available and required feed weights and stabling facilities (taken as constants in southern Ontario) to support cattle of a given type. This comparison technique, within the model, yields an output of farm type and actual numbers of cattle. The accuracy of prediction so obtained is high and is independent of the location or attributes of the widely spaced sample areas.

abstract: Thesis

abstract: Master of Arts (MA)


title: The Effects of Additives on the Fracture Toughness of Magdol

contributor:
Nicholson, P. S.
Metallurgy and Materials Science

subject: additives, fracture toughness, Magdol, magnesia, enriched doloma, microcracks

abstract:
 The effects of small additions of Fe2O3, GeO2, Ta2O5, V2O5, TiO2, and SiO2 on the microstructure and fracture toughness of magnesia enriched doloma were investigated. Effects of up to 5% additive oxides on grain growth and sintering in MgO and CaO were determined in preliminary tests. One percent additions were made to 40%, 60% and 80% MgO dolomas and the fracture toughness at temperatures up to 1500°C determined using the single edge notched beam specimen. Fracture surfaces were studied on the scanning electron microscope to determine fracture mode. Silica and Ta2O5 doped material showed high toughness at 1500°C possibly due to microcracks, while TiO2 resulted in formation of a viscous grain boundary film producing high toughness at 1300°C followed by a rapid decline by 1500°C. In undoped samples increases in MgO resulted in the appearance of a toughness peak near
1300°C. This was attributed to grain boundary segregation of impurities.

abstract: Thesis

abstract: Master of Engineering (MEngr)


title: The Role of Astrocyte-Secreted Thrombospondin-1 in the Fragile X Mouse Model

contributor:
Doering, Laurie C.
Neuroscience

abstract: Fragile X syndrome (FXS) is the most common inherited form of intellectual disability and autism spectrum disorders. The disorder is typically caused by decreased or absent levels of the fragile X mental retardation protein (FMRP) due to a loss-of-function mutation in the fragile X mental retardation 1 (FMR1) gene. Astrocytes are key participants in various aspects of brain development and function, many of which are executed via secreted proteins. Specifically, the astrocyte-secreted matricellular protein thrombospondin-1 (TSP-1) has been highly implicated in the regulation of neuronal synaptogenesis. Previously, we have shown that astrocytes can prevent the abnormal dendrite morphology and dysregulated synapses that characterize FXS. While we have identified that astrocytes affect synapse development in vitro, the role of secreted factors has not been elucidated. Utilizing a Fragile X mouse model and a neuron-astrocyte, non-contact co-culture system, we investigated the contributions of soluble TSP-1 in spine and synapse development. We found that TSP-1 protein levels were reduced in Fmr1 knockout (KO) cultured astrocytes and astrocyte-conditioned media (ACM). TSP-1 levels were also downregulated in the cortex and hippocampus of Fragile X mice in contrast to their wildtype (WT) counterparts. Additionally, Fmr1 KO hippocampal neurons exhibited significant deficits in dendritic spine morphology and excitatory synapse formation following long-term culture. However, all spine and synaptic abnormalities were prevented in the presence of either ACM or a feeder layer derived from WT astrocytes, or following the application of exogenous TSP-1, thereby suggesting a role for soluble glial factors in the formation and maturation of spines and synapses. These findings presented here provide strong evidence for astroglia-derived TSP-1 as a strong promoter of neuronal development in FXS. Therefore, defects in astrocyte function and secreted molecules during early development may contribute to the abnormal neurobiology in FXS.

abstract: Dissertation

abstract: Doctor of Philosophy (PhD)


title: Synthesis and Biosynthesis of Mimosine

contributor:
Spenser, I. D.
Chemistry

subject: synthesis, biosynthesis, Mimosine, debenzylation, aspartic acid

abstract: DL-Mimosine has been synthesized by debenzylation and detosylation of the product obtained by condensation of 3-benzyloxy-4-pyrone with β-amino-α-tosylaminopropionic acid. A new method for the isolation of mimosine from Leucaena glauca Benth. is described. The biosynthesis of mimosine was studied by feeding radioactive aspartates, glycerol, glycerate and ribose to Mimosa pudica L. . Mimosine-C^14 was isolated and partially degraded, and it was shown that the carbon-3 of aspartic acid is specifically incorporated into the pyridone ring.

abstract: Thesis

abstract: Doctor of Philosophy (PhD)


title: EXPLOITING COLD SENSITIVITY IN ESCHERICHIA COLI TO IDENTIFY NOVEL ANTIBACTERIAL MOLECULES

title: BACTERIAL COLD STRESS AND ANTIBIOTIC DISCOVERY

contributor:
Brown, Eric David
Biochemistry and Biomedical Sciences

subject:
cold stress
ribosome biogenesis
outer membrane
lipopolysaccharide

abstract: The widespread emergence of antibiotic resistance determinants for nearly all drug classes threatens human health on a global scale. It is therefore essential to discover antibiotics with novel functions that are less likely to be influenced by pre-existing resistance mechanisms. An emerging approach to identify inhibitors of investigator-defined cellular processes involves screening compounds for antimicrobial activity under non-standard growth conditions. Indeed, by growing cells under conditions of stress, inhibitors of specific cellular targets can be enriched, thereby allowing for the identification of molecules with predictable activities in the complex environment of the cell. Here, I exploit cold stress in Escherichia coli to identify molecules targeting ribosome biogenesis and outer membrane biosynthesis. First, through a screen of 30,000 small molecules for growth inhibition exclusively at 15°C, I was able to identify the first small molecule inhibitor of bacterial ribosome biogenesis, lamotrigine. Second, by leveraging the idiosyncratic cold sensitivity of E. coli to vancomycin, I developed a novel screening technology designed to enrich for non-lethal inhibitors of Gram- negative outer membrane biosynthesis. From this platform, I identified pentamidine as an efficient outer membrane perturbant that was able to potentiate Gram-positive antibiotics against Gram-negative pathogens, similar to the polymyxins. Remarkably, however, this compound was able to overcome mcr-1 mediated polymyxin resistance. Together, this thesis highlights the utility of exploiting the bacterial cold stress response in antibiotic discovery.

abstract: Thesis

abstract: Doctor of Philosophy (PhD)


title: Reactions of Pyridoxine

contributor:
Spenser, I.D.
Chemistry

abstract: Title: Reactions of Pyridoxine, Author: Frederick J. Rowell, Location: Thode

abstract:
The chemistry of pyridoxine has been critically
examined with a view to obtaining new intermediates suitable for
the systematic degradation of the molecule. Use has been made of
three new degradation schemes arising from this work to isolate
atoms C-2 , C-2 ', C- 4, C- 4' and C-5' of radioactive pyridoxine
obtained from feeding experimen ts . · The biosynthesis of pyridoxine
is discussed in the light of the degradation results which demonstrate
that pyridoxine is derived from three molecules of glycerol.

abstract: Thesis

abstract: Master of Science (MS)


contributor:
Radforth, N.W.
Botany

abstract: Title: A Preliminary Structural and Micropalaeobotanical Investigation of some Uppermost Cretaceous Coals from Western Canada, Author: Glenn E. Rouse, Location: Thode

abstract: A preliminary examination of the structural features and plant microfossils which characterize coals from thin seams in the Uppermost Cretaceous formation of western Alberta. Descriptions of the structural units and microfossils are complemented by quantitative appraisals of plant microfossil associations. Suggestions of probable floral components which existed during Uppermost Cretaceous imps and possibilities of seam correlation and separation are forwarded. Illustrated by five photographic plates.

abstract: Thesis

abstract: Candidate in Philosophy


contributor:
Calvo, C.
Chemistry

abstract: Title: The Crystal Structure of Selenourea at 20°C and ar -100°C, Author: John S. Rutherford, Location: Thode

abstract:
The trigonal form of selenourea has been
examined by X-ray crystallographic methods both at room temperature
and at a lower temperature ( -100°C) . The lattice parameters of
earlier workers have been refined and the space group assignment,
which requires nine crystallographically distinct SeC(NH2)2
molecules, confirmed. The crystal structure was solved using a
novel Patterson technique and differences Fourier syntheses, and
was refined by least squares using three - dimensional data obtained
0 at -100°C. Both the molecular dimensions and the crystal structure
found are compared to other members of the urea series, and the
similarity of the crystal structure to the urea- and thioureahydrocarbon
complexes discussed. Evidence is presented of N-H...Se
hydrogen bonds, supporting their recent discovery in chemically
related compounds.

abstract: Thesis

abstract: Doctor of Philosophy (PhD)


title: Newton-Okounkov Bodies of Bott-Samelson & Peterson Varieties

contributor:
Harada, Megumi
Mathematics and Statistics

subject:
Newton-Okounkov bodies
Bott-Samelson varieties
Peterson varieties
Hessenberg varieties
flag variety
standard monomial theory

abstract:
The theory of Newton-Okounkov bodies can be viewed as a generalization of the theory of toric varieties; it associates a convex body to an arbitrary variety (equipped with auxiliary data). Although initial steps have been taken for formulating geometric situations under which the Newton-Okounkov body is a rational polytope, there is much that is still unknown. In particular, very few concrete and explicit examples have been computed thus far.

In this thesis, we explicitly compute Newton-Okounkov bodies of some cases of Bott-Samelson and Peterson varieties (for certain classes of auxiliary data on these varieties). Both of these
varieties arise, for instance, in the geometric study of representation theory.

Background on the theory of Newton-Okounkov bodies and the geometry of flag and Grassmannian varieties is provided, and well as background on Bott-Samelson varieties, Hessenberg varieties, and Peterson varieties. In the last chapter we also discuss how certain techniques developed in this thesis can be generalized. In particular, a generalization of the flat family of Hessenberg varieties constructed in Chapter 6, which may allow us to compute Newton-Okounkov bodies of more general Peterson varieties, is an ongoing collaboration with H. Abe and M. Harada.

abstract: Thesis

abstract: Doctor of Philosophy (PhD)


title: A Climatology of Black Bay

contributor: Civil Engineering and Engineering Mechanics

abstract: Title: A Climatology of Black Bay, Author: Francis E. Roy, Location: Thode

abstract:
Black Bay is a major hatchery for lake herring (Coregonus
artedii, Leseur) on the North shore of Lake Superior. Selgeby (1978)
observed and documented the rapid spring dispersal of herring larvae.
This preliminary study has been directed towards the identification of
some of the mechanisms of this dispersal. It is based on data
obtained from two specifically set current meter stations and a
bathythermograph survey conducted in the spring of 1978, as well as
data from existing meteorologic and stream flow records. A spectral
analysis of the current meter record was done to determine the main
energy components of the flow. Evidence indicates that transports in
the Bay are driven by several mechanisms which are common to coastal
estuaries, including a psuedo-tide, river inflow, and circulation due
to longitudinal density (thermal) gradients, as well as surface
winds. It is proposed that the passage of the thermal bar through the
Bay may also be a significant influence on the dispersal of the
herring larvae. The distinct seasonal character of the climatology is
evident, though more data is needed to properly document it. Reasons
for the attractiveness of the Bay to the herring as a hatchery are
suggested, as is one vulnerability of the system to contamination by
surface run-off.

abstract: Thesis

abstract: Master of Engineering (ME)


contributor:
Brockhouse, B.N.
Physics

abstract: Title: Crystal Dynamics and Anharmonic Properties of Bi-Pb-Tl Alloys, Author: Aditya P. Roy, Location: Thode

abstract:
The crystal dynamics and anharmonic properties have
been investigated in disordered alloys of Bi-Pb-Tl using slow
neutron spectrometry. Damping of phonons caused by phonon-phonon
interaction and the effect of the force constant
disorder on the lifetime of the phonons have been studied in
the alloys. Measurements of the coefficients of thermal
expansion are reported. An experimental method of determining
the lattice frequency spectra by coherent inelastic scattering
of neutrons from polycrystalline materials is described.

abstract: Thesis

abstract: Doctor of Philosophy (PhD)